Diseases and ConditionsEnd Stage Renal Disease (ESRD)
METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA helps your body make more red blood cells. This medicine is used to treat anemia caused by chronic kidney failure.
They need to know if you have any of these conditions:
anemia caused by cancer chemotherapy
blood clotting disorders
hemoglobin level of 12 g/dL or greater
high blood pressure
history of stroke or blood clots
low levels of iron, folate, or vitamin B12
an unusual or allergic reaction to Methoxy polyethylene glycol-epoetin beta, mannitol, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine is for injection into a vein or under the skin. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Visit your prescriber or health care professional for regular checks on your progress and for the needed blood tests and blood pressure measurements. It is especially important for the doctor to make sure your hemoglobin level is in the desired range, to limit the risk of potential side effects and to give you the best benefit. Keep all appointments for any recommended tests. Check your blood pressure as directed. Ask your doctor what your blood pressure should be and when you should contact him or her.
As your body makes more red blood cells, you may need to take iron, folic acid, or vitamin B supplements. Ask your doctor or health care provider which products are right for you. If you have kidney disease continue dietary restrictions, even though this medication can make you feel better. Talk with your doctor or health care professional about the foods you eat and the vitamins that you take.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blood clots in your hemodialysis vascular access device
changes in vision
confusion, trouble speaking or understanding
feeling faint or lightheaded, falls
high blood pressure
pain, swelling, warmth in the leg
sudden numbness or weakness of the face, arm or leg
swelling of the ankles, feet, hands
trouble walking, dizziness, loss of balance or coordination
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
irritation at site where injected
Keep out of the reach of children.
If you are using this medicine at home, you will be instructed on how to store this medicine. Store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). If a refrigerator is unavailable, the prefilled syringes may be stored at room temperature (up to 77 degrees F [25 degrees C]) for up to 30 days. Vials may be stored at room temperature for up to 7 days. Throw away any unused portion. Do not freeze or shake. Protect from light. Throw away unused medicine after the expiration date on the label.